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Upcoming Events

WBF Executive Summit Conference on Procedure-Based Manufacturing,
April 23, 2009
Embassy Suites Hotel, Rosemount, IL

Previous Events

Orlando, FL
September 21-23, 2009

www.mesa.org

"Manufacturing Science Model Extensions to Address Lean Manufacturing and Lean Supply Chain"

Velumani Pillai, Rob Burrows, Dennis Brandl

Innovation in manufacturing with faster development, faster new product release, robust process understanding and vastly improved quality by design is critical for advanced manufacturing organizations. Lean manufacturing and supply chain optimization are increasingly important elements of advanced manufacturing organizations and capturing information to support these efforts is an important part of product and process definitions.
Manufacturing science is the body of scientific knowledge, regulations and principles involved in the transformation of materials and information into products. We have proposed Manufacturing Science Informatics (MSI) as the new information model framework to support Process and Product Knowledge discovered, shared, retained and applied over a product’s entire life-cycle. MSI framework enables established business processes such as production sourcing, material sourcing, new product introduction, continuous process improvement, process optimization and product investigations, but can also be extended to address new business processes. MSI Framework uses ISA 88 General Recipes as one of the foundational information entities.
Lean manufacturing is the elimination of non-value added operations and elimination of waste in production. Lean manufacturing requires an unambiguous definition of production and process options, expected yields, and maximum expected waste, so that site specific lean decisions can be made.
Lean Supply chain is the optimizing the sourcing of materials and supplier networks. This require an unambiguous definition of material substitutions, production and process options, and expected processing times and throughputs, so that sourcing and supply chain execution decisions can be made.
 


2009 European Conference
November 10-12, 2009
Barcelona
, Spain
www.wbf.org

"Tutorial on the ISA 88 Standard"

"Manufacturing Science Model Extensions to Address Lean Manufacturing and Lean Supply Chain"


Automation and Process Control: Smart Approaches for Implementing State-of-the-Art Technologies
February 26, 2008
Hyatt Regency, Tampa FL

www.ispe.org

"ISA 95 - The New Models for MES and EBRs in Life Science Industries"

As pharmaceutical companies move from paper to electronic records and paper work instructions to electronic work instructions they are faced with a bewildering array of choices and different vendor solutions. Many pharmaceutical companies are moving to the ISA 95 models for Manufacturing Operations Management to bring structure and order to MES, LIMS, Maintenance Management, and Material Movement control. They are using the ISA standard as the structure for their requirements and as the method to compare vendor proposals. The standards are also being used to effectively integrate multiple different MES and LIMS systems to the corporate ERP system in a consistent manner. The integration methods, based on XML technology, isolate the peculiarities of ERP and MES systems, allowing upgrades and changes without impacting the interfaces or other systems.

2008 North American Conference
March 24-26, 2008
Philadelphia, PA
www.wbf.org

"What’s Above a Master Recipe, work flows in MES systems?"

The ISA 88 standard provides a powerful model for effective operations and control at the Process Cell and Master Recipe level, but says nothing about the levels above. The ISA 95 standard provides activity models and data exchange models, but does not tie these into the ISA 88 model. This paper discusses how the new models in the ISA 95 updated standard, Work Segments and Work Definitions, can bridge the gap between the ISA 95 models and the ISA 88 models, providing an easy to understand and well integrated solution to the ISA 88 problem, what is above the master recipe. The paper proposes the use of Work Definitions to define the routing of batches between process cells, production lines, storage, and production units. It shows how each of the elements within a Work Definition are used to define product (or general work) specific instructions for an MES area level work flow engine. The paper proposes a natural progression and hierarchy of activities that relate the well defined ISA 88 structures to the well defined ISA 95 structures and defines a robust work flow instruction model.

2008 North American Conference
March 24-26, 2008
Philadelphia, PA
www.wbf.org

"Manufacturing Science Model Extensions to Address Product and Process Sustainability"

Velumani Pillai, Rob Burrows, Dennis Brandl

Innovation in manufacturing with faster development, faster new product release, robust process understanding and vastly improved quality by design is critical for advanced manufacturing organizations. Sustainability awareness (the environment and societal impact of the product and production processes) is also permeating into consumer’s minds in evaluating products. Manufacturing science is the body of scientific knowledge, regulations and principles involved in the transformation of materials and information into products. We proposed Manufacturing Science Informatics (MSI) as the new information model framework to support Process and Product Knowledge discovered, shared, retained and applied over a product’s entire life-cycle. MSI framework enables established business processes such as production sourcing, material sourcing, new product introduction, continuous process improvement, process optimization and product investigations, but can also be extended to address new business processes. MSI Framework uses ISA 88 General Recipes as one of the foundational information entities. Emerging sustainability and green directives (such as EU Directive 2005/32/EC) are placing new reporting and assessment demands such as total and actual energy use and greenhouse gas emissions be tracked and reported not only during design but also manufacturing of a product. Sustainability criteria is increasingly finding its way into development and sourcing decisions. Here we propose extensions to the ISA 88 General Recipe model and other product and process information entities in the ISA 95 standards to handle these evolving needs.

Seminars Industrial Networking

Clearer Process Understanding: From R&D to Manufacturing - Making PAT Work for You
Hosted by Siemens Energy and Automation
February 19, 2008
North Carolina Biotechnology Center, RP NC
www.sea.siemens.com/automationevents

"Integrating PAT with Batch Management Systems "

Dennis Brandl

PAT, Process Analytical Technology, is becoming more widespread in the life science industries. Advanced sensor technology and sophisticated signal processing provide a window into previously hidden aspects of the process. These sensors allow improved real time monitoring and control, enhanced process knowledge and control capability, continuous quality monitoring, measurement of all ‘Critical to Quality’ attributes lending more confidence to regulators, providing data for exception analysis, and all real-time end point control of processes. Implementing PAT in a system with batch execution capabilities requires changes to the recipes and to the underlying equipment model, because of the improved control capabilities. This presentation will discuss the typical methods used in Batch Management systems that follow the ISA 88 standard for Batch Control to include PAT capabilities. The methods include extensions to the corporate process definitions that can be maintained in General and Site recipes and handling additional process control and reporting capability in equipment model definitions. These changes are consistent with the ISA 88 models and demonstrate how PAT can be integrated within existing commercially available batch execution systems.

 

MESA 2005 Plant2Enterprise Conference
September 26-29, 2005
Rosen Plaza Hotel, Orlando, FL
www.mesa.org

"B2MML and SAP – Business to Manufacturing Integration"  (4 Hour Seminar)

The WBF B2MML schemas are becoming a popular method for ERP to MES integration, especially for companies integrating MES to SAP R3 systems.  The B2MML schemas are being used by control system vendors, ERP vendors, and directly by end users to simplify and speedup integration projects.   This seminar will be a detailed focus on the B2MML schemas for material definitions, product definitions, production schedules and production performance, with a special focus on mapping to SAP R3 information.  The material and product definitions are used to integrate shop floor systems with material masters, BOMs, and inventory accounting systems.  The production schedule and production performance reports are used to integrate shop floor systems with advanced planning systems, supply chain systems, inventory systems, and production cost accounting systems.  The seminar will include an explanation of the meaning and structure of the B2MML elements and discuss specific implementations and SAP mappings used in projects.  The seminar will also include an explanation of the design decisions made in creating the B2MML schemas and will identify the steps involved and recommended practices for developing corporate extensions to the schemas.


YOKOGAWAYokogawa 2005 User Conference and Exhibition
Capital Hilton, Washington DC
August 29 – September 1, 2005
www.yokogawa.com

"Enterprise Integration using the ISA 95 Standard and B2MML Schemas"

Integration of business systems to shop floor systems is an important final phase in an ERP implementation.  Companies are discovering that the true value in a logistics system only comes when it is connected to real world shop floor information.  The ISA 95 and IEC 62264 standards define the terminology for business to manufacturing integration.  The WBF B2MML (Business to Manufacturing Markup Language) defines an implementation that is emerging as the preferred method for integration.  This session will provide an overview of the ISA 95 standard and the WBF B2MML schemas.


ISA Seminar on PAT
ISA Research Triangle Park, NC
November 1, 2005
www.isa.org


"Continuous Improvement and Knowledge Management Tools"

The FDA PAT initiative requires that life science companies take a new approach to knowledge management.  Previously individual expertise has been used to calculate key and critical production parameters to achieve the desired key and critical product quality attributes.  Once these parameters were calculated, such as mixing speed, mixing time, granulation pressure, etc, they were followed in all future production.   PAT provides the opportunity to optimize product by predicting quality based on in-line or on-line measurements that relate to end quality.  This means that previous individual knowledge has to be documented and managed.  PAT uses knowledge management tools to structure and document process knowledge discovered during validation, investigations, and optimizations.  This session will discuss the issues and solutions for effective Knowledge Management for PAT initiatives. 


MESA International Conference
September 13-16, 2004
Indian Lakes Resort Metro Chicago area
Title: "ISA 95 Implementations and the New Models for Collaborative Production Management (CPM)"

                            www.mesa.org/conference/2004/index.htm

 

www.aspenworld2004.com
Title: "The IT Implications of S95"

 

ISA EXPO 2004
Automation + Control Conference, Training and Exhibition
5-7 October 2004
Reliant Center, Houston, Texas

www.appcluster05.com/instrumentation2004splash.cfm

 

World Batch Forum, North American 2004 Conference
May 16-19, 2004
Marriott's Lincolnshire Resort
Chicago, IL

www.wbf.org

 

26 August 2003 - Computer System Compliance (CSC) Technology
Research Triangle Park NC
"Preparing for GMP Audits"

www.isa.org

 

7-9 September, 2003 - MESA International
Chicago IL
Tuesday September 9th - "Enterprise and Plant Floor Integration - the Role of the ISA-S95 Standard"

www.mesa.org/conference

 

25-26 September 2003 - Operational Excellence in Consumer Packaged Goods Manufacture
Queens College, Cambridge University, UK
Friday September 26th - "Manufacturing Operations Management"
www.iee.org

University of Cambridge PowerPoint presentation